朝の時間帯にコーヒーを飲むことが、死亡リスク低下と強く関連
コーヒーを飲むタイミングが朝型の人は、飲まない人と比較して、全死亡および心血管死リスクが有意に低い
米テュレーン大学公衆衛生熱帯医学大学院のXuan Wang氏らは、米国民がコーヒーを飲むタイミングのパターンを特定し、死亡率との関連を検討した。この観察研究の対象者には、1999～2018年の米国国民健康栄養調査（NHANES）に参加した成人4万725人と、Women's and Men's Lifestyle Validation Study（WLVSおよびMLVS）に参加した成人1,463人が含まれた。
コーヒーを飲むタイミングは、NHANESで朝型（対象者の36％）と終日型（対象者の14％）の2パターンが特定され、WLVSおよびMLVSでも同パターンが検証された。中央値9.8年の追跡期間中に、全死亡4,295人、心血管死1,268人、がん死亡934人が確認された。朝型パターンの人では、カフェイン入りおよびカフェイン抜きコーヒーの摂取量、睡眠時間、その他の交絡因子で調整した後も、コーヒーを飲まない人と比較して、全死亡および心血管死のリスクが有意に低下した（ハザード比はそれぞれ0.84、0.69）。コーヒー摂取量と全死亡との関連は、コーヒーを飲むタイミングによって有意に変化した。朝型パターンの人では、コーヒー摂取量が多いほど全死亡リスクが有意に低下した。
著者らは、「われわれの研究結果は、コーヒー摂取量と健康アウトカムとの関連において、飲むタイミングを考慮することの重要性を強調している」と述べている。
Drinking Coffee in Morning More Strongly Linked to Lower Mortality Risk
Morning-type pattern significantly linked to lower risks for all-cause and cardiovascular disease-specific mortality compared with non-coffee drinking
WEDNESDAY, Jan. 8, 2025 (HealthDay News) -- Coffee drinking timing is associated with all-cause and cardiovascular disease-specific mortality risk, according to a study published online Jan. 8 in the European Heart Journal.
Xuan Wang, M.D., Ph.D., from the School of Public Health and Tropical Medicine at Tulane University in New Orleans, and colleagues identified patterns of coffee drinking timing in the U.S. population and examined their association with mortality. The observational study included 40,725 adults from the National Health and Nutrition Examination Survey 1999 to 2018 and 1,463 adults from the Women's and Men's Lifestyle Validation Study.
Two distinct patterns of coffee drinking timing were identified in the National Health and Nutrition Examination Survey and were validated in the Women's and Men's Lifestyle Validation Study: morning type (36 percent of participants) and all-day type (14 percent of participants). The researchers noted 4,295 all-cause deaths, 1,268 cardiovascular disease deaths, and 934 cancer deaths during a median follow-up of 9.8 years. The morning-type pattern was significantly associated with lower risks for all-cause and cardiovascular disease-specific mortality compared with non-coffee drinking (hazard ratios, 0.84 and 0.69, respectively) after adjustment for caffeinated and decaffeinated coffee intake amounts, sleep hours, and other confounders. The association between coffee intake amounts and all-cause mortality was significantly modified by coffee drinking timing; in those with a morning-type pattern, higher coffee intake amounts were significantly associated with a lower risk for all-cause mortality.
"Our findings highlight the importance of considering drinking timing in the association between the amounts of coffee intake and health outcomes," the authors write.
European Heart Journal Editorial